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Funded PhD Student Position:
Investigation of Brain Fluid Dynamics for Non-Invasive Identification of Treatable Dementia

The differentiation between currently not treatable types of dementia, such as caused by Alzheimer’s disease, and treatable types, e.g. due to hydrocephalus, is of high clinical importance. Despite advances in medical imaging, clear differential diagnosis requires invasive procedures for many patients. Since only specialized centers offer such tests, misdiagnoses occur and patients are wrongly labeled as terminally ill.

In a project funded by the Swiss National Science Foundation, we aim to study the physiologic basis of a new, non-invasive method for the identification of treatable forms of dementia caused by cerebrospinal fluid pathologies. The project combines computational modeling of fluid dynamics in the brain and spinal canal, physiologic tests on healthy human volunteers, and combined invasive and non-invasive measurements on patients.

We are seeking a doctoral student for the computational part of the project, which will include the design of a computational physiologic model of dynamic fluid distribution in the central nervous system, taking into account the interaction of the cerebrospinal fluid with the cardiovascular and respiratory systems. The student will also contribute to the physiologic tests on healthy volunteers. S/he will furthermore participate in the analysis of data acquired on patients, working in close collaboration with our partners at ETH Zurich and the University Hospital Bern.

We are particularly looking for candidates with strong background in systems modeling, preferably with experience in computational physiology, systems biology and fluid dynamics. Ideally, the candidates will also have a fundamental understanding of human physiology and anatomy. Excellent oral and written English language skills are mandatory. German language skills are not required, but of advantage.

Please send your complete application electronically to Prof. Vartan Kurtcuoglu. We request a letter of motivation, your CV, three names of references with e-mail addresses, a list of publications (if any), plus transcripts of BSc and MSc grades or equivalent.

 

Research Fellow, Post-Doctoral and PhD Student Positions

If you would like to pursue a topic within our research area and are willing to acquire funding for that work, please contact Prof. Kurtcuoglu to explore options.

 

Semester, Bachelor and Master Projects

We are looking for talented students to join our team. You can find an overview of currently open projects here.