Studienarbeiten

  • Computational Physiology / Cardio-Renal Axis

    A funded doctoral position in the general areas of computational physiology and biomedical engineering is available at the Interface Group of the Institute of Physiology, University of Zurich, Switzerland. more
  • Characterization and comparison of different DNA amplification methods

    In this master thesis, we explore the suitability of recombinase polymerase amplification (RPA) for our experimental needs and compare its performance to equivalent polymerase chain reaction (PCR) experiments. more
  • A gas driven pump system for physiological flow

    This project aims at creating a new pumping system that can provide continuous physiologically accurate flow waveforms without the unwanted oscillations present in current state of the art pumping systems. more
  • A gas driven pump system for continuous flow

    This project aims at creating a new pumping system that can provide continuous physiologically accurate flow waveforms without the unwanted oscillations present in current state of the art pumping systems. more
  • Meningothelial cell response under flow conditions

    This project aims to characterize the meningothelial cell response under flow conditions. This includes the study of proliferation, uptake, secretion and trans-cellular transport. more
  • Modeling of Mitochondrial Membrane Potential Fluctuations

    Mitochondria are often referred to as the power plants of cells. When they malfunction, cells are in trouble. One way to assess mitochondrial function is by analysis of their membrane potential. But what happens with this potential when several mitochondria are in contact and interact? Do healthy mitochondria help their damaged peers? The goal of this project is to find answers to these questions using mathematical modeling. more
  • Modelling red blood cell deformation in a rotary blood pump

    Patients with end-stage heart failure require transplantation or mechanical assist devices supporting their heart’s function. This master/semester project aims at implementing a sophisticated multiphase CFD model for such an assist device. more
  • Mechanosensing in Neurons

    Clues in experimental brain research suggest that the brain is likely to be mechanically active and that neurons respond to shear stress in their environment. This project aims to demonstrate such mechanosensing in neurons. more
  • Determining indicators of erythrocyte damage in vitro

    Patients with end-stage heart failure require transplantion or need mechanical circulatory support, e.g. by ventricular assist devices (VAD). One problem that often arises is mechanical blood damage within the pump. This master project aims at the development of an experimental setup for the investigation of hemolysis in VADs. more
  • Simulation of Blood Flow in a Realistic Numerical Phantom using Computational Fluid Dynamics

    In this project, the functional information of the blood flow in the aorta is simulated with CFD methods and realistic flow fields are extracted. This allows for the investigation and testing of compensation methods that are indispensable for the measurement of blood flow using non-invasive Magnetic Resonance Imaging techniques. more
  • Acute hemodynamic impact after mitral valve correction: unveil the mystery of the Afterload Mismatch

    This project explored the physiological mechanisms underlying the onset of afterload mismatch, which remains a major issue after mitral valve repairs. more
  • Development of a dynamic bioreactor for cancer metastasis research

    Metastasis is the primary cause of cancer-related death. The aim of this project is to design and build a dynamic bioreactor to study the interaction of cancer, endothelial and white blood cells in a controlled environment. This is a joint project with the ETH Zürich, Institute of dynamic systems and control. more
  • Determining the role of mechanical stimuli in blood-brain barrier opening

    Ultrasonically excited intravascular microbubbles are an innovative tool to locally open the blood-brain barrier (BBB) for drug delivery purposes. This project aims to assess the relationship between the stresses generated by their vibrations and the increase in BBB permeability. more
  • Development of a dynamic bioreactor for cancer metastasis research

    Metastasis is the primary cause of cancer-related death. The aim of this project is to design and build a dynamic bioreactor to study the interaction of cancer, endothelial and white blood cells in a controlled environment. This is a joint project with the ETH Zürich, Institute of dynamic systems and control. more
  • Anatomical Investigation of Kidney Vasculature through Corrosion Casting and Micro-CT Analysis

    This project is motivated by the lack of information on the complex structure of the kidney vasculature. In this project, the student will perform corrosion casting on kidneys of mice or rats and will analyze the casted specimens with micro-CT. more
  • Atlas of the parenchymal micro-structure

    The objective of this Master’s project is to construct an atlas of the brain’s microstructure using available literature data and determine a strategy to gather missing information. Information of interest includes cellular types, density and spatial organization in different regions of the brain, mechanical properties, and structural differences between normal and hydrocephalic brains. more
  • Design of a dynamic bioreactor for cancer metastasis research

    Metastasis is the primary cause of cancer-related death. The aim of this project is to design and build a dynamic bioreactor to study the interaction of cancer, endothelial and white blood cells in a controlled environment. This is a joint project with the ETH Zürich, Institute of dynamic systems and control. more