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Systems Biology aims at the quantitative analysis and predictive mathematical modeling at all levels of biological organization. The aim of this interdisciplinary PhD program of systems biological researchers of the University of Zurich and ETH Zurich is to train students from various disciplines and departments including Computer Science, Biological Sciences, and Engineering to become future leaders in Systems Biology. The program provides students with the generic skills for working in this new scientific field as well as training in project-specific aspects of their PhD work.